The Truth About Prescription Weight Loss Medications — Benefits & Side Effects
- Dr. Zack Ferris

- 13 hours ago
- 3 min read

Introduction
In today’s fast-paced world, obesity and excess weight have become common health challenges. Many people struggle to lose weight through diet and exercise alone, leading them to seek prescription medications for additional support. These anti-obesity drugs can be effective for certain individuals — but they’re not magic pills. Understanding how they work, their benefits, and their side effects is essential before starting any treatment. In this blog, we uncover the truth about prescription weight loss medications — offered or recommended by Skymeds can be effective for certain individuals — but they are not magic pills.
What Are Prescription Weight Loss Medications?
Prescription weight loss medications (also known as anti-obesity drugs) help manage obesity or overweight conditions when lifestyle changes alone aren’t enough. These medicines target different aspects of weight regulation such as appetite control, fullness, or fat absorption.
How Do Weight Loss Medications Work?
1. Appetite Suppressants
These medicines act on the brain to reduce hunger and increase satiety. Examples:
Phentermine (appetite suppressants)
Diethylpropion
Bupropion/Naltrexone (Contrave)
2. Fat Absorption Inhibitors
These reduce the amount of fat your body absorbs. Example:
Orlistat (fat absorption inhibitors) — blocks enzymes that break down dietary fats.
3. GLP-1 Receptor Agonists
Newer medications mimic natural hormones that regulate appetite and blood sugar. Examples:
Semaglutide (Wegovy, Ozempic)
Liraglutide (Saxenda) (GLP-1 agonists)
4. Combination Medications
Two active ingredients are combined for better results. Example:
Phentermine/Topiramate (Qsymia)
Benefits of Prescription Weight Loss Medications
1. Effective Weight Loss
Most people lose 5–15% of body weight within 6–12 months with proper use.
2. Improved Metabolic Health
Helps reduce:
Blood pressure
Cholesterol
Blood sugar
3. Increased Motivation
Seeing results boosts confidence and encourages healthy habits.
4. Better Quality of Life
Improved mobility, energy, and overall well-being.
Common Side Effects
1. Gastrointestinal Issues
More common with Orlistat:
Oily stools
Flatulence
Frequent bowel movements
2. Nervous System Effects
Seen with Phentermine:
Restlessness
Insomnia
Increased heart rate
3. Nausea & Vomiting
Common in GLP-1 receptor agonists like Semaglutide or Liraglutide.
4. Mood Changes
Some may experience anxiety or mood shifts (Bupropion/Naltrexone).
5. Serious Side Effects (rare)
High blood pressure
Liver issues
Gallstones (from rapid weight loss)
Pancreatitis
Who Should Take These Medications?
✔ Candidates
You may qualify if:
BMI ≥ 30, or
BMI ≥ 27 with conditions like diabetes, hypertension, or sleep apnea
You’ve tried lifestyle changes for at least 6 months
👉Skymeds always recommends a personalized evaluation before starting weight loss medications.
❌ Avoid If:
Pregnant or breastfeeding
History of heart disease or uncontrolled hypertension
Taking interacting medications
Severe psychiatric issues
Tips for Safe & Effective Use
Consult Your Doctor — essential for safe treatment.
Combine with a Healthy Lifestyle — diet + exercise = best results.
Follow Dosage Instructions — never self-increase.
Track Your Progress — weight, BMI, mood, symptoms.
Be Patient — sustainable weight loss takes time.
When to Stop Weight Loss Medication
If you haven’t lost at least 5% of your body weight after 12 weeks, Skymeds may suggest stopping or switching medications. Long-term use is only recommended if it remains effective and safe.
Final Thoughts
Prescription weight loss medications can be a powerful tool for individuals struggling with obesity. However, they work best when combined with healthy habits, consistent exercise, and regular medical supervision. Always consult a qualified healthcare professional before starting or stopping any medication.
FAQs
1. Are prescription weight loss pills safe?
Yes, under medical supervision. Skymeds evaluates health and prescribes the right option.
2. Can they be used long-term?
Some, like GLP-1 drugs, are safe for long-term use depending on your doctor’s advice.
3. Will I regain weight after stopping?
Possibly — if lifestyle habits are not maintained.
4. Do I need a diet while using them?
Yes — balanced nutrition is essential.
5. Can these medications cure obesity permanently?
No — they help manage weight; long-term success requires lifestyle changes.
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